TY - JOUR TI - The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for gXe research AU - Kirkbride, James B. T2 - Social Psychiatry and Psychiatric Epidemiology AB - In this commentary I review the recent paper by Iyegbe et al. on "The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for gXe research". I discuss how the paper advances our knowledge of polygenic risk scores for use, amongst others, in gene-environment interaction studies and the opportunities and challenges such approaches will bring to our understanding of the epidemiology of psychotic disorders, including schizophrenia. DA - 2014/10// PY - 2014 DO - 10.1007/s00127-014-0961-6 DP - NCBI PubMed VL - 49 IS - 10 SP - 1531 EP - 1534 J2 - Soc Psychiatry Psychiatr Epidemiol LA - eng SN - 1433-9285 ER -